Occupational exposure to hydrazines

criteria for a recommended standard by National Institute for Occupational Safety and Health. Division of Criteria Documentation and Standards Development

Publisher: U.S. Dept. of Health, Education and Welfare, Public Health Service, Center for Disease Control, National Institute for Occupational Safety and Health, Publisher: for sale by the Supt. of Docs., U.S. Govt. Print. Off. in [Cincinnati, Ohio, Washington, D.C

Written in English
Published: Pages: 269 Downloads: 561
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Subjects:

  • Hydrazines -- Physiological effect,
  • Hydrazines -- Toxicology,
  • Industrial hygiene -- Standards -- United States,
  • Industrial safety -- Standards -- United States

Edition Notes

Other titlesCriteria for a recommended standard, occupational exposure to hydrazines, NIOSH criteria for a recommended standard, occupational exposure to hydrazines
Statement[Division of Criteria Documentation and Standards Development, National Institute for Occupational Safety and Health].
SeriesDHEW publication -- no. (NIOSH) 78-172
ContributionsS.R.I. International
Classifications
LC ClassificationsRC963.3 N3848
The Physical Object
Paginationviii, 269 p. :
Number of Pages269
ID Numbers
Open LibraryOL22313449M

  [24] “ Criteria for a Recommended Standard: Occupational Exposure to Waste Anesthetic Gases and Vapors,” Centers for Disease Control and .   NIOSH Criteria for a Recommended Standard: Occupational Exposure to Hydrazines, U.S. Department of Health, Education, and Welfare, Publ. (NIOSH) (). NIOSH/OSHA Occupational Health Guidelines for Occupational Hazards, U.S. Department of Health and Human Services, Publ. (NIOSH) (), available as GPO Stock # from. Other hydrazines may interfere. OTHER METHODS: This method is a modification of and replaces Method S [2]. Method P&CAM is a gas chromatographic method which can be used for quantitation of hydrazine or substituted hydrazines [3]. Methods S, S and S utilize a non-specific colorimetric method for substituted hydrazines [4]. School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, BC Epidemiologic Studies Related to Exposure to Hydrazines: TABLE Selected Epidemiologic Studies—Health Outcomes and Exposure to Hydrazines: Show this book's table of contents.

Hydrazine Use in the Military: Health Effects, Exposure Limits, and Protection Guidelines. Hydrazine (N 2 H 2) is an inorganic compound used in industrial the military, hydrazine is used in various rocket fuels and as a propellant onboard space vehicles, such as the NASA Dawn probe to . HSE Books, Sudbury, Suffolk CO10 6FS, United Kingdom. CancerChem (). Version Electronic database of U.S. Public Health Service Publication Occupational Exposure to Hydrazines. DHEW (NIOSH) Publication No. U.S. Department of Health, Education, and Welfare, Public Health Service, Centers. TLVs and BEIs Book and OEV Guide Combo Set. Limited Supply While They Last! AVAILABLE SOON! PRE-ORDER TODAY! This new set includes the TLVs ® and BEIs ® book, a user-friendly, pocket-sized book used worldwide as a guide for evaluation and control of workplace exposures to chemical substances and physical agents, and the Guide to Occupational Exposure Values, . The National Institute for Occupational Safety and Health recommends that the level of hydrazine in workplace air not exceed parts of compound per million parts of air ( ppm) for a 2 h period. The Occupational Safety and Health Administration (OSHA) limits the amount of hydrazine in workplace air to 1 ppm for an 8 h workday.

Exposure to heat can cause illness and death. Learn of precautions your employer should take any time temperatures are high and the job involves physical work. 2 pages (OSHA - . Re-evaluation Of Some Organic Chemicals, Hydrazine And Hydrogen Peroxide, Parts 1,2,3 (IARC MONOGRAPHS ON EVAL OF CARCINOGENIC RISK TO HUMANS) by IARC, , WORLD HEALTH ORGANIZATION edition, Paperback in English - 1 edition. In addition, Bullock has been an adjunct instructor in the Division of Environmental and Occupational Health, Emory University’s Rollins School of Public Health since Bullock is the co-author of A Practical Approach to Exposure Assessment Programs in the Private Sector, Applied Occupational and Environmental Hygiene Volume 16(2):

Occupational exposure to hydrazines by National Institute for Occupational Safety and Health. Division of Criteria Documentation and Standards Development Download PDF EPUB FB2

Hazard Summary. Individuals may be exposed to hydrazine in the workplace or to small amounts in tobacco smoke. Symptoms of acute (short-term) exposure to high levels of hydrazine may include irritation of the eyes, nose, and throat, dizziness, headache, nausea, pulmonary edema, seizures, and coma in humans.

Criteria for a Recommended Standard: Occupational Exposure to Hydrazines. June DHHS (NIOSH) Publication Number This Criteria Document is contained in PDF files, for ease of handling. The following table of contents allows you to open or download the files containing the sections of the document you want to see.

The aim was to examine the cause specific mortality of men exposed to hydrazine. Hydrazine was produced at a factory in the east midlands between and The cohort of.

Of the three lung cancer cases in the high-exposure group, two occurred in workers with less than two years of occupational exposure to hydrazine. This study has been recently extended for A text screen explains the dangers of short term exposure to hydrazine (). Symptoms include: dizziness and nausea, skin burns or eye damage, and even unconsciousness.

Another text screen explains the dangers of long term exposure (), which can result in kidney damage, liver damage, and potentially cancer. In principle, the systemic genotoxicity of hydrazine, based on such an indirect mechanism, may be characterised by a threshold at low exposure levels (when hydrazine-induced DNA methylation.

Several government Occupational exposure to hydrazines book agencies have taken action to protect people from excess exposure to hydrazines.

EPA considers hydrazine and 1,1- dimethylhydrazine to be hazardous air pollutants. The Occupational Safety and Health Administration (OSHA) limits the amount of hydrazine and 1,1- dimethylhydrazine to and ppm, respectively, in. Given that hydrazine exposure was based on jobs listed in employment records, subjects who switched jobs in the company and thus had varied levels of exposure may have diluted the effects of stratification presented by person-years.

Hydrazine is an odorless, fuming, oily liquid with an ammonia-like odor. Because of hydrazine’s potential carcinogenic hazard, NIOSH (e/Ex. ; Ex. ) has recommended that workplace exposures to hydrazine not exceed ppm, as determined by a two-hour air sample; this level represents the lowest detectable concentration over this sampling period.

Occupational exposure to hydrazine and subsequent risk of cancer. By N Wald, J Boreham, Occupational exposure to hydrazines book Doll and J Bonsall.

Abstract. Four hundred and twenty seven men with varying degrees of occupational exposure to hydrazine, a weak animal carcinogen, were studied to see if they provided any evidence of carcinogenicity to man. The observed mortality was. Criteria for a Recommended Standard: Occupational Exposure to Hydrazine DHHS (NIOSH) Publication No.

()– Presents a standard to prevent the adverse effects of exposure to hydrazine over a. Occupational exposure to hydrazines: treatment of acute central nervous system toxicity.

Aviat Space Environ Med ; – Exposure to hydrazine and hydrazines’ alkylated derivatives is an important occupational health issue, which will increase in significance as space applications increase.

The results weigh against there having been any material hazard of occupational exposure to hydrazine. The small number of men studied means, however, that a.

Diamine, Hydrazine (anhydrous), Hydrazine base Colorless, fuming, oily liquid with an ammonia-like odor.

[Note: A solid below 36°F.]. Occupational exposure to hydrazine and subsequent risk of cancer. Morris J(1), Densem JW, Wald NJ, Doll R.

Author information: (1)Wolfson Institute of Preventive Medicine, St Bartholomew's Hospital Medical College, London. Measurements indicate compliance with a Time Weighted Average value of ppm hydrazine, however, potential peak exposures which range as high as 5 to 8 ppm do occur during some tasks.

A technician would be unaware of many such exposures since concentrations below the odor threshold of 3 to 5 ppm give no warning but are at least an order of magnitude above acceptable occupational exposure limits. Four hundred and twenty seven men with varying degrees of occupational exposure to hydrazine, a weak animal carcinogen, were studied to see if they provided any evidence of carcinogenicity to man.

The observed mortality was close to that expected for lung cancer, other cancers, and all other causes, irrespective of the level of exposure.

The exposure level of employees in eight plants was estimated based on the concentration of hydrazine in the air and the potential absorption through the skin. The questionnaire was sent to power plants and were returned, of which used hydrazine. Occupational exposure to hydrazine and subsequent risk of cancer.

Wald N, Boreham J, Doll R, Bonsall J. Four hundred and twenty seven men with varying degrees of occupational exposure to hydrazine, a weak animal carcinogen, were studied to see if they provided any evidence of carcinogenicity to man.

METHODS--Hydrazine was produced at a factory in the east midlands between and The cohort of all men who were employed there for at least six months with varying degrees of occupational exposure to hydrazine were followed up until the end of January   NIOSH recommends that employee exposure in the workplace to hydrazine, methylhydrazine, 1,1-dimethylhydrazine, 1,2-dimethylhydrazine, and phenylhydrazine, and their salts formed by addition with acids, such as sulfates, hydrochlorides, or hydrobromides, be controlled by adherence to the following sections.

The standard is designed to protect the health and provide for the. Concentrations of hydrazine in controlled atmospheres were not verified by an independent method.

Average collection efficiency at L/min for six bubblers was at mg/m 3. Average recoveries from HCl solution wereand at theand µg levels of hydrazine. Furthermore, an analysis of occupational exposure to hydrazine by Koizumi et al. () indicated that repeated 8 h/day exposure to hydrazine at ppm did not result in signs of toxicity.

The AEGL-2 was based upon data showing the induction of nasal lesions following a single 1-h exposure of rats to ppm hydrazine (Latendresse et al. occupational exposure to hydrazine. The small number of men studied means, however,thatarelativerisk ashigh 3'5 for lung cancer cannot confidently be excluded.

(OccupEnvironMed;) Keywords: occupationalexposure; hydrazine; cancer Hydrazine (NKH4) is a colourless, fuming, oily liquid with an ammonialike odour. It is used as a. Abstract A case of systemic lupus erythematosus-like disease due to occupational exposure to hydrazine is described. The patient had four of the revised criteria for SLE (malar rash, photosensitivity, antinuclear antibody, and antibody to nDNA) and genetically is a.

This chemical inventory is OSHA's premier one-stop shop for occupational chemical information. It compiles information from several government agencies and organizations.

Information available on the pages includes: Chemical identification and physical properties Exposure limits Sampling information. Details: Corporate Authors: National Institute for Occupational Safety and Health.

Division of Criteria Documentation and Standards Development. Description: "NIOSH recommends that employee exposure in the workplace to hydrazine, methylhydrazine, 1,1-dimethylhydrazine, 1,2-dimethylhydrazine, and phenylhydrazine, and their salts formed by addition with acids, such as sulfates, hydrochlorides, or.

Human occupational data and studies in laboratory animals suggest that people exposed to hydrazines may develop adverse systemic health effects or cancer.

Hydrazines have caused cancer in animals following acute- or intermediate-duration exposure by the oral and inhalation routes. Occupational exposure to hydrazines. Corporate Authors: National Institute for Occupational Safety and Health.

Division of Criteria Documentation and Standards Development. Published Date: June Series: Criteria for a recommended standard DHEW publication ; no. (NIOSH)   Health service is an important work area which can lead to important risks related to occupational health and safety (OHS) of employees.

This book chapter is prepared to evaluate the effects of occupational risks on health and decrease the exposure to occupational risks of health professionals by searching national and international literatüre.

For USAF personnel, Air Force Occupational Safety and Health (AFOSH) StandardAttachment 8 reviews the considerations for occupational exposure to hydrazine in missile, aircraft and spacecraft systems. Specific guidance for exposure response includes mandatory emergency shower and eyewash stations and a process for decontaminating protective clothing.

Purpose Hydrazine is carcinogenic in animals, but there is inadequate evidence to determine if it is carcinogenic in humans. This study aimed to evaluate the association between hydrazine exposure and the risk of lung cancer. Methods The cause specific mortality rates of a cohort of men who were employed at an English factory that produced hydrazine between and.

Hydrazine derivatives and induction of systemic lupus erythematosus. J Am Acad Dermatol Wald N, Boreham J, Doll R, et al. Occupational exposure to hydrazine and subsequent risk of cancer.

Br J Ind Med Morris J, Densem JW, Walk NJ, et al. Occupational exposure to hydrazine and subsequent risk of cancer.